It's not clear what causes celiac disease, which is also known as celiac sprue, nontropical sprue and gluten-sensitive enteropathy. Doctors know that something happens in people with celiac disease to cause the body's immune system to overreact in response to gluten in food.
Normally, your small intestine is lined with tiny, hair-like projections called villi. Resembling the deep pile of a plush carpet on a microscopic scale, villi work to absorb vitamins, minerals and other nutrients from the food you eat. Celiac disease results in damage to the villi. Without prominent villi, the inner surface of the small intestine becomes less like a plush carpet and more like a tile floor, and your body is unable to absorb nutrients necessary for health and growth. Instead, nutrients such as fat, protein, vitamins and minerals are eliminated with your stool.
While the exact cause of celiac disease is unknown, doctors have discovered that it often runs in families. If someone in your family has been diagnosed with celiac disease, you may have an increased risk of the disease. Researchers have discovered that some gene mutations seem to increase the risk of celiac disease, but having those gene mutations doesn't mean you're certain to have celiac disease. This means that other risk factors play a role in whether you'll develop celiac disease.
Source: Mayoclicnic.com
Normally, your small intestine is lined with tiny, hair-like projections called villi. Resembling the deep pile of a plush carpet on a microscopic scale, villi work to absorb vitamins, minerals and other nutrients from the food you eat. Celiac disease results in damage to the villi. Without prominent villi, the inner surface of the small intestine becomes less like a plush carpet and more like a tile floor, and your body is unable to absorb nutrients necessary for health and growth. Instead, nutrients such as fat, protein, vitamins and minerals are eliminated with your stool.
While the exact cause of celiac disease is unknown, doctors have discovered that it often runs in families. If someone in your family has been diagnosed with celiac disease, you may have an increased risk of the disease. Researchers have discovered that some gene mutations seem to increase the risk of celiac disease, but having those gene mutations doesn't mean you're certain to have celiac disease. This means that other risk factors play a role in whether you'll develop celiac disease.
Source: Mayoclicnic.com
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